Description
Cytiva NanoAssemblr Blaze Nanoparticle Formulation System NIB0038
The NanoAssemblr™ Blaze system enables the process development of LNPs including early CMC studies and large-scale protocol development of upstream and downstream operations, providing valuable insights into processes and consumables required for GMP manufacturing.
- Efficient: Verify end-to-end clinical manufacturing processes including tangential flow filtration (TFF), sterile filtration, and fill/finish operations on a preclinical system with a simplified setup and shorter run times, saving time and resources.
- Flexible volume: Select Blaze™ for low-volume applications of up to 1 L or upgrade to Blaze+™ for high-volume applications of up to 10 L, enabling toxicity, stability, and large-cohort in vivo animal studies.
- Closed system environment: Assess manufacturing processes in a closed system environment on the Blaze+™ system, which enables external vessel connections and includes a software upgrade, minimizing risk during scale-up.
- Scalable: Efficient technology transfer of critical process parameters (CPPs) to the NanoAssemblr™ commercial formulation system and a cGMP facility.
- Reproducible: NxGen™ technology ensures controlled mixing conditions, resulting in consistent flow rates for robust particle formation.
In good working condition, images form part of the description.
Specification:
- Volume: 10 to 1000ml
- Reagent ratio: 1: to 1:5
- Total flow rate: 4 to 115ml/min
- Weight: 127kg
- Dimensions: 89 x 47 x 65cm (w x d x h with closed lid)
- Electric supply: 100 to 240V 50/60Hz
